Without any doubts, today the number of overweight people is constantly increasing. And there are plenty of reasons of this epidemic. The most common causes of people’s obesity are inactive lifestyle and unhealthy eating habits. As a result, these people have physical health problems and loss of productivity. They also suffer from stress and tiredness. The obvious question is — what should people do to slim?
Certainly, daily exercising helps people to build a regular and healthy habit for physical activity. However, some of them make a vital mistake, when they are on a diet or even jump into this new lifestyle that they’re never going to manage to sustain. And sometimes these workouts aren't so realistic. If your work week is hectic, you might choose other effective ways that cause weight gain. There are a number of weight loss pills that have credible science behind. Let’s discuss some of them.
According to official figures, these pills helped people with obesity lose a significant amount of their weight. So, more than 85% of adults on Semaglutide managed to cut at least 5% of their baseline body weight. During the first 4 weeks of taking the treatment initiation, people on Semaglutide had more than a 2% reduction in body weight, and then continued to lose flesh throughout the 68-week trial.
Besides, it improved cardiovascular risk factors with greater reductions in waist circumference, BMI, systolic and diastolic blood pressures, HbA1c, fasting plasma glucose, C-reactive protein, and fasting lipid levels, as well as physical functioning scores and quality of life.
The licensed indication for Semaglutide includes the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise. Evidence from the Semaglutide study has been submitted to drugs regulators for approval as a treatment for obesity. This means it cannot be routinely prescribed.
Moreover, Professor Sir Stephen O'Rahilly, from the University of Cambridge, said: "The amount of weight loss achieved is greater than that seen with any licensed anti-obesity drug.
To start with, Rybelsus is a hormone that occurs naturally in our body, and it is also a synthetic compound that is designed to work similarly. It has a special addition called salcaprozate sodium, which facilitates the absorption of the drug after it is taken orally.
People with a higher initial body weight and those experiencing more digestive symptoms may be more likely to lose weight once treatment with Rybelsus has started. Its use has shown really impressive improvements in both blood glucose concentrations and A1c, as well as reductions in weight. In clinical studies, Rybelsus reduced weight loss of up to 4.4kg (~10 lbs).
Although it is not a weight loss drug, lots of people lose flesh. According to the statistics, they lose, on average, five pounds (2.3kg) while taking Rybelsus 7mg and 8.1 pounds (3.7kg) while taking Rybelsus 14mg. One of the ways Rybelsus works is by helping to make people feel full after a meal. Actually, it’s an oral medicine that is used to improve blood sugar control in adults over the age of 18 with type 2 diabetes. It is often prescribed after oral medications for diabetes have not worked or have stopped working.
Semaglutide is also the active drug in a brand-name medication called Ozempic. It is always associated with low risk of low blood glucose. Its main benefit is effective weight loss up to 13 lbs, which is greater than reports from other GLP-1 RAs on the market.
As for results from a 56-week medical study, it is said that more than 1000 adults with 2 diabetes did lose their weigh. However, some patients did gain weight.
People’s blood glucose levels have to begin to fully decline within the first week after they start using Ozempic at their regular maintenance dose. Nevertheless, the full effect may take 8 weeks or even longer, as this is a long-acting medication that is injected only once per week.
In addition to the fact that Rybelsus is practically the same as Ozempic in pill form, the majority of doctors and researchers expect that to be positive. That is why, if patients have heart disease, their doctor recommends Ozempic instead of Rybelsus. In fact, Ozempic is approved to decrease the risk of negative heart events in people with type 2 diabetes and heart problems. However, Rybelsus isn't approved for this use.